Telomeres shorten as we get older causing aging in our cells
We inherit telomeres from our parents, but no matter the length of our
telomeres at birth, everyone’s get shorter as they age. 4,6
Shorter telomeres have a negative effect on our health.4,8
Telomere shortening is the main cause of age-related break down of our
When telomeres get too short, our cells can no longer reproduce, which
causes our tissues to degenerate and eventually die.1,4
Some cells, like those found in the skin, hair and immune system, are most
affected by telomere shortening because they reproduce more often.4,6
Short telomeres have been connected to premature cellular aging3,8
Mounting evidence shows a strong connection between short telomeres
and aging in our cells3,4,5
There is scientific evidence that telomeres can be lengthened
An enzyme called telomerase can slow, stop or perhaps even reverse
the telomere shortening that happens as we age.2,5
The amount of telomerase in our bodies declines as we age.4
Telomerase maintains and may even lengthen telomeres.2,5,6
Exposing human cells to telomerase slows cell aging and allows
cells to begin copying again2 and
longer telomeres cause gene expression to change to a younger
phenotype which makes cells function as though they were younger.
There are other things we can do that might help restore telomere
length or at least slow the loss of telomere length: reduce
stress, stop smoking, lose weight, exercise more and eat a
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degeneration in aged telomerase-deficient mice. Nature.
Sahin E, DePinho RA. Linking functional decline of telomeres,
mitochondria and stem cells during ageing. Nature.
Blackburn EH, Epel ES. Comment: Too toxic to ignore. Nature.
Eisenberg DTA. An evolutionary review of human telomere biology:
the thrifty telomere hypothesis and notes on potential adaptive
paternal effects. American Journal of Human Biology.
Oeseburg H, et al. Telomere biology in healthy aging and disease.
Pflügers Archiv – European Journal of Physiology.
Aubert G, Lansdorp PM. Telomeres and aging. Physiological Reviews.
Ornish D. Effect of comprehensive lifestyle changes on telomerase
activity and telomere length in men with biopsy-proven low-risk
prostate cancer: 5-year follow-up of a descriptive pilot study.
The Lancet Oncology. 2013;14(11):1112–1120.
Armanios M, Blackburn EH. The telomere syndromes. Nature Reviews
Kaszubowska L. Telomere shortening and ageing of the immune
system. Journal of Physiology and Pharmacology. 2008;59(Suppl
Valdes AM, et al. Telomere length in leukocytes correlates with
bone mineral density and is shorter in women with osteoporosis.
Osteoporosis International. 2007;18(9)1203–1210.
Valdes AM, et al. Obesity, cigarette smoking, and telomere length
in women. The Lancet. 2005;366(964)662–664.